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Study identifier: NCT07416604 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

Condition: Hemophilia A  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants360
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of NXT007 prophylaxis compared with emicizumab prophylaxis in people age 12 years and older with severe or moderate congenital hemophilia A without factor VIII (FVIII) inhibitors or with hemophilia A of any severity (severe, moderate, and mild) with FVIII inhibitors.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: BO45887 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. Only)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (12)

Center for Inherited Blood DisordersOrange, California, United StatesRecruiting
Innovative Hematology, Inc.Indianapolis, Indiana, United StatesRecruiting
University Of Iowa Hospitals And ClinicsIowa City, Iowa, United StatesRecruiting
Washington Center for Bleeding DisordersSeattle, Washington, United StatesRecruiting
The Chaim Sheba Medical Center - PPDSRamat Gan, Central District, IsraelRecruiting
Nagoya University HospitalNagoya, Aiti, JapanRecruiting
Gunma University HospitalMaebashi, Gunma, JapanRecruiting
Nara Medical University HospitalKashihara-shi, Nara, JapanRecruiting
Ogikubo HospitalSuginami-Ku, Tokyo, JapanRecruiting
Hospital Universitario La Paz - PPDSMadrid, SpainRecruiting
Hospital Regional Universitario de Malaga ? Hospital GeneralMálaga, SpainRecruiting
Hospital Universitari i Politecnic La Fe de ValenciaValencia, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07416604