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Study identifier: NCT07416526 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

Condition: Hemophilia A  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants126
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of NXT007 prophylaxis compared with Factor VIII (FVIII) prophylaxis in participants with severe or moderate congenital hemophilia A without inhibitors. The study will include people aged ≥12 years old with severe or moderate congenital hemophilia A without inhibitors on previous FVIII prophylaxis treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: WO45886 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. Only)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (2)

Nara Medical University HospitalKashihara-shi, Nara, JapanRecruiting
Tokyo Medical University HospitalShinjuku-Ku, Tokyo, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT07416526