Condition: Duchenne / Becker Muscular Dystrophy · Dystrophia Myotonica 1 · Congenital Myopathies · Sponsor: University Hospital, Clermont-Ferrand
The study aims to find out if a specific blood molecule called miR-1, can be used as a biomarker to track the health of patients with certain muscle diseases. MicroRNAs (miRs) are small messengers that help control how cells grow and stay healthy. Some of these, like miR-1, are specifically found in muscles and the heart. Research shows that levels of miR-1 are often abnormal in people with muscle-wasting conditions, but more information are needed to understand how this relates to the severity of the disease. The main goal is to compare the blood levels of miR-1 between four different groups at different ages and severities: 1. Patients with Duchenne or Becker muscular dystrophy (DMD/DMB). 2. Patients with Myotonic Dystrophy Type 1 (Steinert's disease). 3. Patients with congenital myopathies. 4. Healthy volunteers (control group). The main objective is to assess if miR-1 levels can accurately show how a muscular disease is progressing.
This description comes directly from the study's public registry record.
Lise Laclautre, PhD · +33473750750 · promo_interne_drci@chu-clermontferrand.fr
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| CHU de Clermont-Ferrand | Clermont-Ferrand, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07415837