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Study identifier: NCT07415551 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 2 Study of Lesigercept in Adult Patients With Chronic Spontaneous Urticaria Who Are Inadequately Controlled by H1-Antihistamines

Condition: Allergic Diseases · Chronic Spontaneous Urticaria (CSU)  ·  Sponsor: Yuhan Corporation

PhasePhase 2
Planned participants150
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study aims to evaluate the efficacy and safety of lesigercept in approximately 150 participants with CSU. By enrolling participants with an inadequate response to H1-antihistamines, including those previously treated with omalizumab, this study is expected to provide evidence for the clinical utility of lesigercept and to further characterize its benefit-risk profile in the target participant population.

This description comes directly from the study's public registry record.

Talk to the study team

JinHyun Choi  ·  +82-2-828-0850  ·  clinicaltrials@yuhan.co.kr

JeungJin Yoon  ·  +82-2-828-0396  ·  clinicaltrials@yuhan.co.kr

Always discuss trial participation with your own doctor first.

Locations (30)

Diagnostic & Consultative Centre Ascendent EOODSofia, Sofia, BulgariaNot Yet Recruiting
UMHAT "Aleksandrovska"Sofia, Sofia, BulgariaNot Yet Recruiting
Medical Center Hera EOODSofia, Sofia, BulgariaNot Yet Recruiting
UMHATEM "N. I. Pirogov"Sofia, Sofia, BulgariaNot Yet Recruiting
Dermatology Hospital of Southern Medical University (Guangdong Province Dermatology Hospital)Guangzhou, Guangdong, ChinaNot Yet Recruiting
The University of Hong Kong-Shenzhen HospitalShenzhen, Guangdong, ChinaNot Yet Recruiting
Alergologia Plus Sp. z o. o.Poznan, Greater Poland Voivodeship, PolandNot Yet Recruiting
Centrum Medyczne ALL-MEDKrakow, Lesser Poland Voivodeship, PolandNot Yet Recruiting
Centrum Nowoczesnych Terapii "Dobry Lekarz" Sp. z o.o.Krakow, Lesser Poland Voivodeship, PolandNot Yet Recruiting
Alergo-Med Ośrodek Badań Klinicznych Sp. z o.o.Tarnów, Lesser Poland Voivodeship, PolandNot Yet Recruiting
ALL-MED Specjalistyczna Opieka MedycznaWroclaw, Lower Silesian Voivodeship, PolandNot Yet Recruiting
DERMACEUM sp. z o.o., DERMACEUM Centrum MedyczneWroclaw, Lower Silesian Voivodeship, PolandNot Yet Recruiting

+ 18 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07415551