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Study identifier: NCT07410676 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Condition: Cancer · Sarcoma · Leukaemia  ·  Sponsor: Essen Biotech

PhasePhase 1/Phase 2
Planned participants83
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This Phase 1/2 study evaluates the safety, tolerability, and preliminary anti-tumor activity of EBNK-001 (allogeneic NK cells) given after lymphodepleting cyclophosphamide/fludarabine (CY/FLU) and supported with low-dose IL-15, administered either alone or in combination with pembrolizumab in adults with advanced/metastatic solid tumors. The study will determine a recommended Phase 2 dose (RP2D) and explore signals of clinical activity using RECIST-based response criteria.

This description comes directly from the study's public registry record.

Talk to the study team

Rhoda M Smith, Phd  ·  2077706670  ·  clinical-trials@essen-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

District One HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07410676