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Study identifier: NCT07410078 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery

Condition: Pediatric Anesthesia · Premedication  ·  Sponsor: Diskapi Yildirim Beyazit Education and Research Hospital

PhaseNA
Planned participants135
Who can joinAll sexes, 4 Years to 12 Years
Healthy volunteersNo

About this study

This prospective, three-arm study aims to evaluate the effects of different oral premedication regimens on venipuncture tolerance in pediatric patients undergoing ambulatory surgery. Children aged 4-12 years scheduled for elective day-case procedures will receive oral midazolam alone, midazolam combined with ibuprofen, or midazolam combined with ketamine prior to anesthesia induction. The primary outcome is the proportion of children with well-tolerated venipuncture, assessed using standardized behavioral and pain scales. Secondary outcomes include anxiety levels, venipuncture success parameters, time to successful intravenous access, and parent and anesthesiologist satisfaction. In cases of inadequate premedication or failed venipuncture, a predefined rescue inhalational induction protocol will be applied to ensure patient safety. The study aims to identify clinically effective premedication strategies that may improve cooperation and reduce distress during intravenous cannulation in pediatric ambulatory anesthesia.

This description comes directly from the study's public registry record.

Talk to the study team

Elif Şule Özdemir Sezgi  ·  00905059209638  ·  elifsule-91@hotmail.com

Aslı Dönmez  ·  00905322256473  ·  aslidonmez@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ankara Etlik City HospitalAnkara, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07410078