Condition: Solid Tumor (Excluding CNS) · Sponsor: Nantes University Hospital
Tumor thermal ablation under Jet Ventilation is a procedure performed under general anesthesia that enables tumor ablation under radiological imaging guidance. This procedure, being less invasive than conventional surgery, allows for a faster recovery and hospital discharge. This procedure requires significant precision to ensure the most complete destruction of the tumor, while also preserving adjacent organs. During general anesthesia, respiratory movements complicate radiological localization and tumor destruction. The principle of High-Frequency Jet Ventilation (HFJV) involves using a device that ventilates a small volume of air and oxygen at a specific pressure, called driving pressure, at a high frequency. This ventilation mode reduces respiratory movements while ensuring continuous ventilation and oxygenation. This respiratory stability allows for the precision necessary to superimpose images for tumor localization and destruction. There are no guidelines regarding the driving pressure setting for HFJV for tumor thermal ablation. The method tested in this research is based on patient's height to optimize the driving pressure when using HFV. The main objective of this research is to evaluate the impact of driving pressure settings, on respiratory function, taking into account patient's height. On the day of the procedure, the driving pressure setting for the HFJV will be randomly assigned (1.4 bars, 1.9 bars, 2.4 bars, or customized according to the patient's heig…
This description comes directly from the study's public registry record.
Nathalie DESFRICHES-DORIA · 0244768434 · nathalie.desfrichesdoria@chu-nantes.fr
Always discuss trial participation with your own doctor first.
| CHU de Lyon | Lyon, France | Not Yet Recruiting |
| Centre Léon Bérard | Lyon, France | Not Yet Recruiting |
| CHU de Nantes | Nantes, France | Recruiting |
| CHU de Nîmes | Nîmes, France | Not Yet Recruiting |
| CHU de Poitiers | Poitiers, France | Not Yet Recruiting |
| ICO Unicancer | Saint-Herblain, France | Not Yet Recruiting |
| Institut Gustave Roussy | Villejuif, France | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07408375