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Study identifier: NCT07408024 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of TollB-001 Tablets in Moderate to Severe Rheumatoid Arthritis

Condition: Rheumatoid Arthritis (RA)  ·  Sponsor: Toll Biotech Co. Ltd. (Beijing)

PhasePhase 2
Planned participants24
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this study is to evaluate the safety, pharmacokinetic (PK) characteristics, and preliminary efficacy of a new oral chemical drug in : adults aged 18-70 years (male or female) with moderate to severe active rheumatoid arthritis (RA), who have had inadequate response to or intolerance of at least one conventional synthetic disease-modifying antirheumatic drug (csDMARDs) . Participants will take the assigned study drug (either tollB-001 Tablets or placebo) once daily orally for 4 weeks, follow up for 1 week.

This description comes directly from the study's public registry record.

Talk to the study team

Weili Wang  ·  +86 10 80710966  ·  wangweili@toll-biotech.com

Always discuss trial participation with your own doctor first.

Locations (6)

The First Affiliated Hospital of Bengbu Medical CollegeBengbu, Anhui, ChinaRecruiting
Peking Union Medical College Hospital, Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting
Puyang Oilfield General HospitalPuyang, Henan, ChinaRecruiting
Affiliated Hospital of Inner Mongolia Medical UniversityHohhot, Inner Mongolia, ChinaRecruiting
Pingxiang People's HospitalPingxiang, Jiangxi, ChinaRecruiting
Linfen Central HospitalLinfen, Shanxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07408024