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Study identifier: NCT07404410 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Robotic Technologies for APATHy in Dementia: a Randomised Controlled Trial (RAPHAel)

Condition: Apathy · Apathy in Dementia  ·  Sponsor: Giovanna Zamboni

PhaseNA
Planned participants75
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this trial is to learn whether home-based robotic interventions can reduce apathy in people with cognitive decline. Apathy means reduced motivation, interest, or initiative in daily life. It is a common and distressing symptom in people with mild cognitive impairment (MCI) or dementia and can strongly affect both participants and their caregivers. This study will compare two different robotic interventions with standard occupational therapy. Researchers want to understand if these new technologies can help people become more engaged, motivated, and involved in everyday activities, and whether they also reduce stress and improve quality of life for caregivers. The main questions this study aims to answer are: * Do robotic interventions reduce apathy more than standard occupational therapy? * Are these robotic interventions easy to use and acceptable for people with cognitive impairment? * Do these interventions reduce caregiver stress and improve caregiver quality of life? Participants will be adults over 40 years of age with a diagnosis of mild cognitive impairment or dementia caused by a neurodegenerative disease, such as Alzheimer's disease, frontotemporal dementia, or dementia with Lewy bodies. All participants must show clinically relevant apathy and have a family member or caregiver who can support them during the study and answer questionnaires. Participants will be randomly assigned to one of three groups: * A telepresence robot group, where participa…

This description comes directly from the study's public registry record.

Talk to the study team

Giovanna Zamboni, MD, DPhil  ·  +393665306279  ·  giovanna.zamboni@unimore.it

Always discuss trial participation with your own doctor first.

Locations (2)

IRCCS "S. Maria Nascente"Milan, Italy, ItalyRecruiting
Azienda Ospedaliero Universitaria di ModenaModena, Italy, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07404410