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Study identifier: NCT07402525 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Postoperative Radiotherapy for Early-stage Oral Tongue Squamous Cell Carcinoma Patients With Risk Factors: a Prospective, Multicenter, Randomized Controlled, Open-labelled Trial

Condition: Oral Tongue Squamous Cell Carcinoma  ·  Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

PhaseNA
Planned participants190
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether postoperative radiotherapy can delay disease recurrence in patients with early-stage oral squamous cell carcinoma who have high-risk factors. The main question it aims to answer is: Is the clinical outcome of early-stage tongue squamous cell carcinoma patients with risk factors after tumor enlargement resection receiving postoperative radiotherapy better than that of patients with simple follow-up observation? How is the safety? Researchers will compare the postoperative radiotherapy group and the simple follow-up observation group to see if there are differences between the two groups in terms of 3-year disease-free survival rate, 5-year disease-free survival rate, overall survival rate, toxicity events, and quality of life. Participants of postoperative radiotherapy group will receive postoperative radiotherapy 6-8 weeks after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (28)

The First Affiliated Hospital of Bengbu Medical UniversityBengbu, Anhui, ChinaNot Yet Recruiting
Cancer Hospital Chinese Academy of Medical SciencesChaoyang, Beijing Municipality, ChinaNot Yet Recruiting
Fujian Cancer HospitalFuzhou, Fujian, ChinaNot Yet Recruiting
Cancer prevention and treatment center, sun yat-sen universityGuandong, Guangdong, ChinaNot Yet Recruiting
Harbin Medical University Cancer HospitalHarbin, Heilongjiang, ChinaNot Yet Recruiting
Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, Hubei, ChinaNot Yet Recruiting
Renmin Hospital of Wuhan UniversityWuhan, Hubei, ChinaNot Yet Recruiting
Hunan Provincial People's HospitalChangsha, Hunan, ChinaNot Yet Recruiting
Hunan cancer hospitalChangsha, Hunan, ChinaNot Yet Recruiting
Jiangxi Cancer HospitalNanchang, Jiangxi, ChinaNot Yet Recruiting
The First Hospital of Jilin UniversityChangchun, Jilin, ChinaNot Yet Recruiting
The First Affiliated Hospital of Dalian Medical UniversityDalian, Liaoning, ChinaNot Yet Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07402525