Condition: Psoriasis (PsO) · Obesity & Overweight · Diabetes Mellitus - Type 2 · Sponsor: Hospital Universitario Dr. Jose E. Gonzalez
This study will evaluate the effects of oral semaglutide in combination with topical corticosteroid/calcipotriol on clinical outcomes and metabolic inflammation in patients with plaque psoriasis and overweight/obesity and/or type 2 diabetes mellitus. A total of 62 participants will be randomized to receive either semaglutide plus topical corticosteroid/calcipotriol or placebo plus topical corticosteroid/calcipotriol for 12 weeks. Clinical efficacy will be assessed using the Psoriasis Area and Severity Index (PASI), and quality of life will be evaluated using DLQI, PROMIS-29, and EQ-5D-5L. Systemic inflammatory markers will also be measured to assess metabolic inflammation.
This description comes directly from the study's public registry record.
Jorge Valdespino, MD · +52 8771093680 · jorge.valdespino@outlook.com
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| Hospital Universitario Dr. José E. González | Monterrey, N.L., Mexico | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07401992