← Eichor
Study identifier: NCT07400471 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy.

Condition: Post Endodontic Pain · Mechanical Detection Threshold · Mechanical Pain Threshold  ·  Sponsor: Chattogram International Dental College

PhaseEARLY_Phase 1
Planned participants280
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

A clinical trial comparing preemptive multimodal analgesics with placebo in the management of immediate and chronic post-endodontic pain. The study utilizes statistical methods such as chi-squared, T-tests, and regression analysis, accounting for multiple outcomes with the Bonferroni adjustment. Duloxetine hydrochloride and pregabalin, both available in Bangladesh, are evaluated as experimental drugs, while placebos are used to assess psychological effects on pain. All participants receive standard interventional treatments, with acetaminophen provided as needed, and ethical considerations are addressed according to international guidelines.

This description comes directly from the study's public registry record.

Talk to the study team

Prof.Dr. Md. Abu Saeed Ibn Harun, MS  ·  8801711157586  ·  dr.abusaeed@cidch.edu.bd

Always discuss trial participation with your own doctor first.

Locations (1)

Professor. Dr. Md. Abu Saeed Ibn HarunChittagong, Chattogram, BangladeshRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07400471