Condition: TAVI(Transcatheter Aortic Valve Implantation) · Sponsor: University Heart Center Freiburg - Bad Krozingen
Severe symptomatic aortic stenosis (AS) with a high gradient is associated with a poor prognosis if not treated with valve replacement. Transcatheter aortic valve implantation has been shown in large randomized trials to be a safe and effective treatment option for patients at low, intermediate, or high risk. Transfemoral access for heart valve replacement is by far the most commonly used approach, as it is relatively easy to control and has a low complication rate compared to other access routes. The TAVI procedure requires two arterial access points: one with a large lumen for the TAVI prosthesis via the femoral artery, and a smaller second one for a pigtail catheter that guides the TAVI prosthesis into the optimal position. This secondary access is most often via a second artery. Vascular complications are the most commonly observed complications in transfemoral TAVI and are associated with poorer procedural outcomes. Recent data suggest that secondary vascular access via the radial artery may contribute to a reduction in vascular complications after TAVI. In patients undergoing coronary angiography and/or percutaneous coronary intervention, radial access has become the preferred strategy due to its proven reduction in vascular complications compared to femoral access. The use of radial access is associated with a lower incidence of vascular complications compared to femoral access. Recent non-randomized data suggest that radial access may be a safer alternative to tra…
This description comes directly from the study's public registry record.
Constantin von zur Muehlen, MD · +49 761 270 34415 · constantin.vonzurmuehlen@uniklinik-freiburg.de
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| University Heart Center - Deparment for Cardiology and Angiology | Freiburg im Breisgau, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07399392