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Study identifier: NCT07397585 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

stereOtactic Body RadIothErapy for exTracranial oligomeTastAtic Breast Cancer: Multi Institutional Retrospective Database

Condition: Breast Cancer · Oligometastasis  ·  Sponsor: Istituto Clinico Humanitas

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Oligometastatic breast cancer is a condition in which breast cancer has spread to a small number of other parts of the body. Patients with this type of disease may live longer than those with more widespread metastases. In addition to standard treatments that act on the whole body, such as chemotherapy or hormonal therapy, these patients might also benefit from local treatments that directly target the cancer spots. One of these local treatments is stereotactic body radiotherapy (SBRT), a non-invasive radiation treatment that delivers high doses of radiation in a few sessions. In the past, most of the evidence about the benefit of local treatments came from surgery. More recently, there has been growing interest in SBRT because it does not require surgery. However, the results of studies so far have not been consistent.The goal of this multicenter retrospective study is to better understand whether SBRT can improve disease control and survival in patients with breast cancer that has spread to a limited number of sites outside the brain.

This description comes directly from the study's public registry record.

Talk to the study team

Ruggero Spoto, MD, Radiation oncologist  ·  +39 0282248508  ·  ruggero.spoto@cancercenter.humanitas.it

Laura Bonavita, Master Degree  ·  +39 0282247026  ·  laura.bonavita@humanitas.it

Always discuss trial participation with your own doctor first.

Locations (28)

Aorn San PioBenevento, Benevento, ItalyNot Yet Recruiting
Humanitas GavazzeniBergamo, Bergamo, ItalyRecruiting
Ospedale PerrinoBrindisi, BR, ItalyNot Yet Recruiting
Spedali CiviliBrescia, BS, ItalyRecruiting
Responsible Research HospitalCampobasso, CB, ItalyRecruiting
Azienda Ospedaliera Universitaria CareggiFlorence, Firenze, ItalyNot Yet Recruiting
Irccs Ospedale Policlinico San MartinoGenova, Genova, ItalyNot Yet Recruiting
A.O.U. "G. Martino" - Università degli Studi di MessinaMessina, Messina, ItalyNot Yet Recruiting
Fondazione I.R.C.C.S Istituto Nazionale Tumori di MilanoMilan, MILANO, ItalyRecruiting
IEOMilan, Milano, ItalyNot Yet Recruiting
IRCCS Humanitas Research HumanitasRozzano, MILANO, ItalyRecruiting
IRCCS Ospedale San RaffaeleMilan, Milan, ItalyNot Yet Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07397585