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Study identifier: NCT07397338 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

Condition: Advanced Solid Tumors · Metastatic Solid Tumors · Non-small Cell Lung Cancer (NSCLC)  ·  Sponsor: Revolution Medicines, Inc.

PhasePhase 1/Phase 2
Planned participants370
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of RAS(ON) inhibitors in combination with ivonescimab in adults with advanced or metastatic solid tumors with a RAS mutation.

This description comes directly from the study's public registry record.

Talk to the study team

Revolution Medicines Study Director  ·  1-844-2-REVMED  ·  medinfo@revmed.com

Always discuss trial participation with your own doctor first.

Locations (6)

Eastern Connecticut Hematology and Oncology AssociatesNorwich, Connecticut, United StatesRecruiting
Tennessee OncologyNashville, Tennessee, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
NEXT DallasIrving, Texas, United StatesRecruiting
NEXT OncologySan Antonio, Texas, United StatesRecruiting
NEXT VirginiaFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07397338