Condition: Acute Respiratory Infection · Influenza-like Illness · Sponsor: Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
The ImpProGUIDE study aims to find out whether implementing new Swiss national guidelines for acute respiratory infections (ARI) can help to reduce antibiotic prescribing in primary care. In Switzerland, most antibiotics are prescribed in outpatient care, and many of these prescriptions may not be needed - especially when infections are caused by viruses, which antibiotics do not treat. Reducing overuse of antibiotics is important to slow the spread of antibiotic resistance. The new guidelines were developed by the Swiss Society for Infectious Diseases (SSI) to support family doctors in managing ARIs, based on a syndromic approach. They recommend the targeted use of point-of-care C-reactive protein (CRP) testing when bacterial infection is suspected, as well as shared decision-making with patients. This study will be carried out in quality circles (QCs) - small groups of family doctors who meet regularly to discuss and improve clinical practice - and in walk-in clinics in French- and Italian-speaking regions of Switzerland. Each will be randomly assigned to either an "intervention" group or a "control" group. In the intervention group, QC moderators and medical center directors will receive implementation resources to lead a session and distribute materials to their group in autumn 2025 on the new guidelines. Doctors can then decide whether or not to use the recommendations in their consultations. In the control group, QCs and centers will continue their regular activitie…
This description comes directly from the study's public registry record.
Jelena Dunaiceva, MPH · +41 78 654 23 74 · jelena.dunaiceva@unisante.ch; imppro@unisante.ch
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| Unisanté | Lausanne, Canton of Vaud, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07396428