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Study identifier: NCT07396233 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis

Condition: Knee Osteoarthristis · Osteearthritis · Knee Pain Arthritis  ·  Sponsor: University of Karachi

PhaseNA
Planned participants150
Who can joinAll sexes, 40 Years to 60 Years
Healthy volunteersNo

About this study

A randomized controlled trial will be conducted at the Department of Physiotherapy, Dr. Ziauddin Hospital and Al-Rayaz Hospital, Karachi, Pakistan. A total of 150 patients diagnosed with knee osteoarthritis, aged between 40-60 years, will be recruited through a non-probability purposive sampling technique. Written informed consent will be obtained from all eligible participants prior to enrollment. The participants will be randomly allocated by the help of computer generated randomization sheet, into two groups i.e. experimental and the control group, with 75 participants in each group. Group A (experimental group) will receive diagonal proprioceptive neuromuscular facilitation (PNF) pattern exercises, while Group B (control group) will receive conventional strength training exercises. Heat therapy will be administered to both groups. All participants will be assessed using a standardized assessment form. Outcome measures will include pain intensity, knee range of motion, functional disability, hamstring flexibility, dynamic balance, and fatigue level. A single blinded assessor will assess all participants at baseline and at post intervention. Treatment sessions will be given thrice a week on alternate days for 6 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Rabia Hassan, MSAPT  ·  +923345448859  ·  rabiahassan096@gmail.com

Basit Ansari, PhD  ·  +923222279221  ·  basitansari@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Al-Rayaz HospitalKarachi, Sindh, PakistanRecruiting
Dr. Ziauddin HospitalKarachi, Sindh, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07396233