Condition: Obesity · Brain Function · Metabolomics · Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
This study is a prospective, single-center, randomized, controlled, crossover intervention trial. A total of 60 participants, including 30 patients with obesity and 30 healthy controls, will be enrolled. Each participant will receive an isocaloric liquid meal challenge (glucose, fat, or protein) on three separate experimental days, with a washout period of at least 7 days between visits to eliminate carryover effects from the previous intervention. The primary objective is to investigate the association between brain functional patterns and plasma metabolic profiles following the ingestion of different macronutrients in patients with obesity, aiming to uncover potential neuro-metabolic imbalance features.
This description comes directly from the study's public registry record.
Yan Bi · 6-25-83-105302 · biyan@nju.edu.cn
Zhou Zhang · 86-25-83-105302 · zhangzhou@smail.nju.edu.cn
Always discuss trial participation with your own doctor first.
| Department of Endocrinology, Endocrine and Metabolic Disease Medical Center,Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University | Nanjing, Jiangsu, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07392905