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Study identifier: NCT07392372 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV

Condition: HIV -1 Infection  ·  Sponsor: BioNTech SE

PhasePhase 1
Planned participants67
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This study will test the safety and blood levels of the antibody BNT351 in people living without and with human immunodeficiency virus (HIV). This study will also test the anti-viral activity of BNT351 in people living with HIV (PLWH) with detectable virus levels. The main goals of this study are: * To learn about the safety of BNT351 and check for side effects. * To measure the amount of BNT351 antibody in blood over time. * To test the amount of HIV in the blood at different times after treatment with BNT351 in people living with HIV.

This description comes directly from the study's public registry record.

Talk to the study team

BioNTech clinical trials patient information  ·  +49 6131 9084  ·  patients@biontech.de

Always discuss trial participation with your own doctor first.

Locations (6)

Cook County HealthChicago, Illinois, United StatesNot Yet Recruiting
Johns HopkinsBaltimore, Maryland, United StatesRecruiting
Washington UniversitySt Louis, Missouri, United StatesNot Yet Recruiting
Columbia UniversityNew York, New York, United StatesNot Yet Recruiting
UK KölnCologne, GermanyRecruiting
CRS MannheimMannheim, GermanyActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT07392372