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Study identifier: NCT07392320 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase II Trial Comparing Immunotherapy Versus Capecitabine Maintenance After Chemo-chemoradiotherapy for High-risk Nasopharyngeal Carcinoma

Condition: Nasopharangeal Cancer  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants142
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

In this study, the investigators designed a randomized, open-label, phase II clinical trial for high-risk locally advanced nasopharyngeal carcinoma (T4 or N3 or EBV DNA ≥1500 copies/ml, AJCC 9th edition) that is sensitive to chemotherapy and PD-1 monoclonal antibody therapy. The trial compares sequential treatment with the TP regimen combined with PD-1 monoclonal antibody followed by concurrent chemoradiotherapy and PD-1 maintenance therapy versus capecitabine maintenance therapy. The aim is to provide high-quality clinical evidence for optimizing the treatment strategy for high-risk locally advanced nasopharyngeal carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Pei-Yu Huang  ·  +86-20-87343379  ·  huangpy@sysucc.org.cn

Qi Yang  ·  yangqi@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07392320