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Study identifier: NCT07392255 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)

Condition: Geographic Atrophy Secondary to Age-related Macular Degeneration  ·  Sponsor: Complement Therapeutics

PhasePhase 1/Phase 2
Planned participants75
Who can joinAll sexes, 55 Years to no upper limit
Healthy volunteersNo

About this study

This is a clinical study to evaluate the safety, tolerability and efficacy of CTx001, administered via a single subretinal injection, for GA (secondary to AMD). Safety and efficacy will be measured at regular intervals for 2 years after which long-term safety will be assessed annually for up to 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Muhammad Ali Memon  ·  clinicaltrials@complementtx.com

Always discuss trial participation with your own doctor first.

Locations (5)

Midwest Eye InstituteCarmel, Indiana, United StatesRecruiting
Sierra Eye AssociatesReno, Nevada, United StatesRecruiting
Retina Foundation of the SouthwestDallas, Texas, United StatesRecruiting
Gundersen Health SystemLa Crosse, Wisconsin, United StatesRecruiting
The Retina Clinic LondonLondon, London, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07392255