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Study identifier: NCT07392242 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia

Condition: Acute Myeloid Leukemia  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 2
Planned participants45
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

The researchers are doing this study to find out whether a 3-drug combination of ivosidenib, azacitidine, and venetoclax followed by maintenance therapy with ivosidenib alone is an effective treatment approach for people with newly diagnosed acute myeloid leukemia (AML) that has an IDH mutation. Maintenance therapy is additional treatment given to help keep cancer from coming back after it has disappeared following the first course of treatment. The researchers will also look at the safety of the treatment approach and what kind of a time commitment it involves for participants.

This description comes directly from the study's public registry record.

Talk to the study team

Kuo-Kai Chin, MD  ·  646-608-4415  ·  chin3@mskcc.org

Eytan Stein, MD  ·  646-608-3749

Always discuss trial participation with your own doctor first.

Locations (7)

Memoral Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activites)Rockville Centre, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07392242