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Study identifier: NCT07391670 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab

Condition: Solid Tumours  ·  Sponsor: AstraZeneca

PhasePhase 1
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of the study is to determine a subcutaneous (SC: under the skin) durvalumab + recombinant human hyaluronidase (rHu) dose that yields systemic drug exposure similar to intravenous (IV: into the veins) durvalumab administration and to evaluate the pharmacokinetics and safety of SC durvalumab + rHu injection in participants with different types of solid tumours (cancers).

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (19)

Research SiteFitzroy, AustraliaNot Yet Recruiting
Research SiteSt Albans, AustraliaNot Yet Recruiting
Research SiteWoolloongabba, AustraliaNot Yet Recruiting
Research SiteBatumi, GeorgiaRecruiting
Research SiteTbilisi, GeorgiaRecruiting
Research SiteTbilisi, GeorgiaRecruiting
Research SiteBrzozów, PolandRecruiting
Research SiteKoszalin, PolandNot Yet Recruiting
Research SiteLublin, PolandRecruiting
Research SiteOlsztyn, PolandRecruiting
Research SitePrzemyśl, PolandRecruiting
Research SiteSeongnam-si, South KoreaRecruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07391670