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Study identifier: NCT07391605 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Descartes-08 in Autoantibody Myositis

Condition: Antisynthetase Syndrome  ·  Sponsor: Cartesian Therapeutics

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a randomized, double-blind, placebo-controlled phase 2 study to evaluate the efficacy, safety and tolerability of an autologous T-cells expressing a chimeric antigen receptor (CAR) directed to B-Cell maturation antigen (BCMA) in patients with autoantibody-mediated myositis, including antisynthetase syndrome (ASyS) and dermatomyositis (DM).

This description comes directly from the study's public registry record.

Talk to the study team

Vera MD  ·  6172318085  ·  trials@cartesiantx.com

Always discuss trial participation with your own doctor first.

Locations (2)

T13Chapel Hill, North Carolina, United StatesRecruiting
T23Austin, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07391605