Condition: Opioid Free Anesthesia · Sponsor: Nashwa Ahmed
Opioid-free anesthesia (OFA) is a multimodal analgesic approach designed to eliminate the intraoperative use of systemic, neuraxial, or intracavitary opioids. This technique employs a combination of antinociceptive agents targeting various pathways within the central and peripheral nervous systems to achieve effective analgesia. Dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist, is a centrally acting non-opioid agent increasingly utilized in clinical practice for its antinociceptive and anxiolytic properties. Only a few prospective randomized controlled trials have specifically examined the postoperative analgesic efficacy of intraoperative dexmedetomidine infusion in patients undergoing spinal surgery, with limited data focusing on this as a primary endpoint. Importantly, no clinical studies have investigated its analgesic impact in patients undergoing spinal surgery under general anesthesia.
This description comes directly from the study's public registry record.
Nashwa gomaa Ahmed, MD · 00201005289328 · dr_nashwa_2008@yahoo.com
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| Port said university | Port Said, Egypt | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07389096