Condition: Respiratory Infections in Old Age · Sponsor: University Hospital, Grenoble
The prevention of infectious diseases in older adults remains a major public health challenge, as acute respiratory infections are a leading cause of hospitalisation, mortality, and functional decline worldwide. Immunosenescence and environmental exposures increase susceptibility to infection and reduce vaccine effectiveness in this population. Respiratory viruses, including influenza, SARS-CoV-2, respiratory syncytial virus, and human metapneumovirus, account for a substantial share of this burden, much of which is vaccine-preventable. However, their impact on functional decline and recovery in older adults remains insufficiently characterized. This international study aims to assess the effect of hospitalization for major respiratory viral infections on loss of autonomy in individuals aged 60 years and older, to inform targeted prevention and vaccination strategies.
This description comes directly from the study's public registry record.
Gaetan GAVAZZI, MD,PhD · 0033(0)476766760 · GGavazzi@chu-grenoble.fr
Saber TOUATI, PhD · 0033(0)476765805 · stouati1@chu-grenoble.fr
Always discuss trial participation with your own doctor first.
| University of Rochester School of Medicine, Infectious Diseases Unit | Rochester, New York, United States | Recruiting |
| University Hospital of Amiens | Amiens, France | Active Not Recruiting |
| Melun Hospital | Melun, France | Recruiting |
| Villeneuve Saint Georges Hospital | Paris, France | Active Not Recruiting |
| University Hospital of Poitiers | Poitiers, France | Active Not Recruiting |
| University Hospital of Reims | Reims, France | Active Not Recruiting |
| University Hospital of Tours | Tours, France | Active Not Recruiting |
| Klinikum Bayreuth, Klinik für Geriatrie | Bayreuth, Germany | Not Yet Recruiting |
| Abteilung Geriatrie Universitätsmedizin Göttingen, Abteilung Geriatrie | Göttingen, Germany | Not Yet Recruiting |
| Uniklinikum Jena, Klinik für Geriatrie | Jena, Germany | Not Yet Recruiting |
| Universitätsmedizin Mannheim, IV. Medizinische Klinik (Geriatrie) | Mannheim, Germany | Not Yet Recruiting |
| Klinikum Ulm, Geriatrisches Zentrum Agaplesion Bethesda | Ulm, Germany | Not Yet Recruiting |
+ 12 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07388173