Condition: Waldenstrom Macroglobulinemia · Lymphoplasmacytic Lymphoma · Sponsor: AbbVie
Lymphoplasmacytic Lymphoma (LPL) is a rare type of low-grade B-cell lymphoma. The purpose of this study is to assess the change in disease activity of adult participants with relapsed or refractory Waldenström macroglobulinemia(WM)/LPL receiving venetoclax. Venetoclax is being investigated in the treatment of WM/LPL. Participants will receive oral venetoclax at doses ramping up to the target dose, as part of treatment. Approximately 14 adult participants with WM/LPL will be enrolled in the study at approximately 20 sites in Japan. Participants will receive oral venetoclax at doses ramping up to the target dose. The total study duration is approximately 28 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, and checking for side effects.
This description comes directly from the study's public registry record.
ABBVIE CALL CENTER · 844-663-3742 · abbvieclinicaltrials@abbvie.com
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| Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital /ID# 279178 | Nagoya, Aichi-ken, Japan | Recruiting |
| Nagoya City University Hospital /ID# 277580 | Nagoya, Aichi-ken, Japan | Recruiting |
| University of Fukui Hospital /ID# 279173 | Yoshida-gun, Fukui, Japan | Recruiting |
| Kyushu University Hospital /ID# 277582 | Fukuoka, Fukuoka, Japan | Recruiting |
| Gunma University Hospital /ID# 277576 | Maebashi, Gunma, Japan | Recruiting |
| Hiroshima University Hospital /ID# 279172 | Hiroshima, Hiroshima, Japan | Recruiting |
| NHO Mito Medical Center /ID# 279175 | Higashiibaraki-gun, Ibaraki, Japan | Recruiting |
| University Hospital Kyoto Prefectural University of Medicine /ID# 277584 | Kyoto, Kyoto, Japan | Recruiting |
| Kindai University Hospital /ID# 277587 | Sakai-shi, Osaka, Japan | Recruiting |
| The University of Tokyo Hospital /ID# 279174 | Bunkyo-ku, Tokyo, Japan | Recruiting |
| National Cancer Center Hospital /ID# 279076 | Chuo-Ku, Tokyo, Japan | Recruiting |
| The Cancer Institute Hospital Of JFCR /ID# 277579 | Koto-ku, Tokyo, Japan | Recruiting |
+ 5 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07387471