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Study identifier: NCT07387198 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Merkel Cell Carcinoma Therapy (Tx) With the PD-1 Inhibitor Cemiplimab

Condition: Merkel Cell Carcinoma, Stage I · Merkel Cell Carcinoma, Stage II · Neoadjuvant Immunotherapy  ·  Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

PhasePhase 2
Planned participants135
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is a randomized, double blind, placebo-controlled, non-comparative phase II trial that investigates the efficacy of neoadjuvant anti-PD-1 antibody Cemiplimab treatment in patients with clinical stage I or II Merkel cell carcinoma who have have undergone primary tumour excision and are pending sentinel lymph node biopsy.

This description comes directly from the study's public registry record.

Talk to the study team

Ralf Gutzmer, Prof. Dr. med.  ·  Ralf.Gutzmer@Muehlenkreiskliniken.de

Michelle Tez  ·  tez.michelle@ikf-khnw.de

Always discuss trial participation with your own doctor first.

Locations (14)

Nationales Centrum für TumorerkrankungenHeidelberg, Baden-Wurttemberg, GermanyRecruiting
Universitätsklinikum MannheimMannheim, Baden-Wurttemberg, GermanyRecruiting
Universitätsklinikum TübingenTübingen, Baden-Wurttemberg, GermanyRecruiting
Universitätsklinikum RegensburgRegensburg, Bavaria, GermanyNot Yet Recruiting
Universitätsklinikum WürzburgWürzburg, Bavaria, GermanyRecruiting
Universitätsklinikum Hamburg-EppendorfHamburg, Free and Hanseatic City of Hamburg, GermanyRecruiting
Universitätsklinikum FrankfurtFrankfurt am Main, Hesse, GermanyNot Yet Recruiting
Klinikum BielefeldBielefeld, North Rhine-Westphalia, GermanyRecruiting
Universitätsklinikum KölnCologne, North Rhine-Westphalia, GermanyNot Yet Recruiting
Universitätsklinikum EssenEssen, North Rhine-Westphalia, GermanyRecruiting
Johannes Wesling Klinikum MindenMinden, North Rhine-Westphalia, GermanyNot Yet Recruiting
Universitätsmedizin MainzMainz, Rhineland-Palatinate, GermanyRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07387198