Condition: Angina (Stable) · Coronary Artery Disease(CAD) · Ischaemic Heart Disease (IHD) · Sponsor: Imperial College London
ORBITA-SOLAR is an invasive physiological cardiac catheterisation study that aims to determine whether different coronary stenoses have different angina thresholds. The angina threshold is defined as the amount of coronary flow reduction required to reproduce symptoms. Sixty patients with symptoms of stable angina and 2 coronary artery stenoses amenable to percutaneous coronary intervention (PCI) will be recruited. This study will use intra-coronary balloon inflation during supine exercise on an ergometer to measure the fractional flow reserve (FFR) and non-hyperemic pressure ratio (NHPR) that relates to angina onset, in real time, at the location of each stenosis.
This description comes directly from the study's public registry record.
Kayla Chiew, MBBS MRCP · 020 7594 5735 · kayla.chiew@imperial.ac.uk
Rasha Al-Lamee, MBBS PhD MRCP · 020 7594 5735 · r.al-lamee13@imperial.ac.uk
Always discuss trial participation with your own doctor first.
| Mid and South Essex NHS Foundation Trust | Basildon, United Kingdom | Recruiting |
| University Hospitals Dorset NHS Foundation Trust | Bournemouth, United Kingdom | Not Yet Recruiting |
| Chelsea and Westminster Hospital NHS Foundation Trust | London, United Kingdom | Recruiting |
| Guy's and St Thomas' NHS Foundation Trust | London, United Kingdom | Not Yet Recruiting |
| Imperial College Healthcare NHS Trust | London, United Kingdom | Recruiting |
| Royal Free London NHS Foundation Trust | London, United Kingdom | Not Yet Recruiting |
| St George's University Hospitals NHS Foundation Trust | London, United Kingdom | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07386418