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Study identifier: NCT07385638 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Olorofim in Early Coccidioidal Meningitis

Condition: Coccidioidal Meningitis  ·  Sponsor: Fariba Donovan

PhasePhase 2
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study is being conducted to learn more about the use of olorofim in Coccidioidal (Cocci) meningitis, a rare but serious fungal infection that affects the brain and spinal cord. The study is exploratory, meaning that early information is being gathered to better understand the effectiveness of olorofim in coccidioidal meningitis in its early stages. The study plans to enroll approximately 10 to 12 participants who have been recently diagnosed-within the last 4 to 8 weeks-and who do not have a ventriculoperitoneal (VP) shunt, a medical device sometimes used to relieve pressure in the brain. Participants will be followed for approximately 6 months, during which health information will be collected to evaluate disease progression and response to treatment. Participants may have the opportunity to enroll in the olorofim Managed Access Program to continue treatment after completion of the study period.

This description comes directly from the study's public registry record.

Talk to the study team

Dakota Darby  ·  5206268000  ·  dakotadarby@arizona.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Banner University Medical CenterTucson, Arizona, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07385638