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Study identifier: NCT07384403 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Application of Topical Oxygen Therapy Around Customized Healing Collar

Condition: Soft Tissue · Healing Abutment Influence on Gingival Volume · Soft Tissue Healing  ·  Sponsor: Cairo University

PhasePhase 4
Planned participants6
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

The preservation and enhancement of peri-implant soft tissues are essential for the long-term success and esthetic integration of dental implants. Customized healing abutments have been introduced to support individualized soft tissue shaping; however, optimizing soft tissue healing around implants remains a clinical challenge. Oxygen plays a critical role in wound healing by promoting angiogenesis, fibroblast proliferation, and collagen synthesis. Topical oxygen therapy has shown promise in accelerating tissue regeneration, yet its application in oral implantology, particularly in conjunction with customized healing abutments, has not been adequately studied. This study aims to provide clinical evidence regarding the effectiveness of topical oxygen therapy in improving linear and volumetric soft tissue changes around dental implants. The findings may guide clinicians in refining soft tissue management protocols and contribute to establishing evidence-based practices in implant dentistry.

This description comes directly from the study's public registry record.

Talk to the study team

Mulhem ahmed, bachelor  ·  00201050202633  ·  mulhem.ahmad@dentistry.cu.edu.eg

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Locations (1)

Cairo universityCairo, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07384403