Condition: Bronchiolitis Acute · Lower Respiratory Tract and Lung Infections · Pediatric Lung Ultrasound · Sponsor: Helse Møre og Romsdal HF
Lower respiratory tract infections (LRTIs) are a significant cause of childhood morbidity and mortality globally, particularly in low-income countries. In Norway, LRTIs is a leading cause of hospitalization among infants, representing a great socioeconomic burden. Bronchiolitis, a viral infection, is the main representation of LRTIs in infants. It affects the small airways, causing breathing- and feeding difficulties. Today, treatment relies on subjective evaluations, lacking objective measures for assessment. This increases the risk of both under- and over treating patients. In the long term, bronchiolitis increases risk of asthma, but it is unknown who the high-risk patients for chronic lung disease are. Lung ultrasonography (LUS) has emerged as a promising tool for assessing bronchiolitis severity and progression of the disease. The investigators will explore its use to improve diagnostic accuracy and treatment decisions, and develop AI-driven scoring tools for novel technology. Additionally, tidal breathing flow volume loops (TBFVL) offer a non-invasive method for evaluating airway obstruction in infants, with the potential to assess severity of bronchiolitis, treatment efficacy and post-infection lung function. In this project the investigators will combine the use of these modern technologies to improve treatment and follow-up of infants with LRTIs. The main aim for this observational study is to assess the utility of lung ultrasonography (LUS) and tidal flow volum…
This description comes directly from the study's public registry record.
Hans Kristian S Ipsen, medical doctor · +4770105000 · hans.kristian.ipsen@helse-mr.no
Kari Risnes, Professor · +4772573000 · kari.risnes@ntnu.no
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| Aalesund Hospital | Ålesund, Møre og Romsdal, Norway | Recruiting |
| St. Olavs Hospital HF | Trondheim, Sør-Trøndelag, Norway | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07381790