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Study identifier: NCT07379684 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections

Condition: Surgical Wound Infection · Traumatic Wound Infection  ·  Sponsor: Macro Biologics, Inc.

PhasePhase 1
Planned participants44
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersNo

About this study

The goal of this Phase 1 clinical trial is to learn about the safety profile of Amicidin-β topical solution applied directly into infected surgical or traumatic wounds during a surgical procedure. The main questions it aims to answer are: 1. Is Amicidin-β topical solution safe to test in larger clinical trials? 2. Is Amicidin-β topical solution absorbed into the bloodstream from local wound application? 3. Is Amicidin-β topical solution easy for the surgeon to use? Participants will receive either standard of care alone, or standard of care with intrawound Amicidin-β topical solution for the management of their wound infection. Researchers will compare these two groups (standard of care alone to standard of care with Amicidin-β topical solution) to see if there are any study drug-related adverse effects.

This description comes directly from the study's public registry record.

Talk to the study team

Daniel J Gowen-Huang, MBA  ·  (323) 717-0302  ·  dgowenhuang@macrobiologics.com

Michael P Bevilacqua, MD, PhD  ·  (303) 881-5169  ·  mpb@macrobiologics.com

Always discuss trial participation with your own doctor first.

Locations (5)

Lundquist InstituteTorrance, California, United StatesRecruiting
Snake River Research, PLLCIdaho Falls, Idaho, United StatesRecruiting
LifeBridge HealthBaltimore, Maryland, United StatesRecruiting
Washington University in St. LouisSt Louis, Missouri, United StatesRecruiting
The Ohio State UniversityColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07379684