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Study identifier: NCT07379190 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN)

Condition: Stroke, Acute · Stroke, Ischemic · Cerebral Infarction  ·  Sponsor: Weifang Medical University

PhasePhase 3
Planned participants458
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to address the existing clinical challenges by introducing high-resolution magnetic resonance vessel wall imaging (HR-MRI), an advanced imaging technology, to achieve precise etiological classification in patients with acute ischemic stroke (AIS) beyond the time window. HR-MRI allows clear visualization of intracranial arterial wall structures and direct identification of key pathological features of the culprit vessel, including atherosclerotic plaques, vascular wall remodeling, and intracranial hemorrhage, thereby enabling reliable differentiation between intracranial atherosclerotic large artery atherosclerosis (ICAS-LAA) stroke and other etiological subtypes such as cardiogenic embolism. Based on the latest clinical demands and advances in imaging technology, this study intends to evaluate the efficacy and safety of tirofiban in patients with ICAS-LAA stroke beyond the time window under the precise guidance of HR-MRI. It is expected to provide high-level evidence-based medical evidence for this specific patient population and further optimize clinical diagnosis and treatment strategies.

This description comes directly from the study's public registry record.

Talk to the study team

Weili Li, MD  ·  86-0536-8192680  ·  wfsrmyy_ky@163.com

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Locations (1)

Weifang People's HospitalWeifang, China/Shandong Province, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07379190