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Study identifier: NCT07378163 Synced from ClinicalTrials.gov · July 29, 2026
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Study on the Preferences for PCI Implantation Devices Among Doctors and Patients

Condition: Coronary Artery Disease · Percutaneous Coronary Intervention  ·  Sponsor: Xijing Hospital

PhaseN/A
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The contemporary percutaneous treatment of coronary artery disease typically involves initial lesion preparation with balloon angioplasty, followed by the deployment of a drug-eluting stent (DES) to provide an immediate scaffold and reduce the long-term risk of restenosis. However, stent implantation continues to present notable challenges, primarily due to the metallic scaffold left behind. Compared to DES, drug-coated balloons (DCB) provide a direct release of antiproliferative drugs into the vessel wall, preventing coronary restenosis after angioplasty and limiting the risk of stent-related events. DCBs are an established treatment option for in-stent restenosis and small vessels. However, the REC-CAGEFREE I trial demonstrated that a strategy of DCB angioplasty with rescue stenting did not achieve non-inferiority compared with the intended DES implantation in patients with de novo, non-complex coronary artery disease (CAD), irrespective of vessel diameter. Previous studies have mainly focused on the efficacy of PCI strategies in reducing adverse event rates, while less attention has been paid to patients' willingness regarding stent implantation. The AHA conducted a systematic review on depression and poor prognosis among patients with acute coronary syndrome (ACS), concluding that health organizations should consider depression as an official risk factor for poor prognosis after ACS. A prior study of patients with coronary artery disease after stent implantation found th…

This description comes directly from the study's public registry record.

Talk to the study team

Ruining Zhang, BSc  ·  +8618629551066  ·  Woshigaochao@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Xijing HospitalXi'an, Shannxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07378163