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Study identifier: NCT07377565 Synced from ClinicalTrials.gov · July 29, 2026
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A First-in-Patient Study to Evaluate the Safety and Tolerability of HB-2121 as a Diagnostic for Celiac Disease

Condition: Celiac Disease  ·  Sponsor: Nielsen Fernandez-Becker

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn about the safety of a single dose of HB-2121 in adults with suspected celiac disease. It will also look at how the drug affects the small intestine. The main questions it aims to answer are: * What side effects do participants have after receiving HB-2121? * How does the drug interact with the small intestine in people with suspected celiac disease? Researchers will follow participants for 30 days after receiving HB-2121 to understand how the drug behaves in the body and how safe it is. Participants will: * Receive one oral dose of HB-2121 four hours before their standard-of-care esophagogastroduodenoscopy * Attend 4 in-person clinic visits for checkups, lab tests, and monitoring * Complete 2 remote visits that include safety lab assessments * Fill out a short daily questionnaire for 7 days about symptoms and health status

This description comes directly from the study's public registry record.

Talk to the study team

Joaquin Tabera  ·  (650) 334-1308  ·  jtabera7@stanford.edu

Marissa Dobry  ·  (313) 320-2240  ·  mdobry@stanford.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Stanford UniversityStanford, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07377565