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Study identifier: NCT07374562 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Stellate Ganglion Block for Long COVID Symptoms: A Randomized Controlled Trial

Condition: Long COVID  ·  Sponsor: Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This single-center, randomized, controlled, single-blind clinical trial evaluates whether a stellate ganglion block (SGB) using bupivacaine can improve persistent symptoms in adults with long COVID. Participants are assigned in a 1:1 ratio to receive either an ultrasound-guided right-sided SGB or a placebo saline injection delivered to the sternocleidomastoid muscle. After the intervention, participants are followed for 26 weeks with scheduled evaluations that include symptom questionnaires and functional tests. The study assesses changes in functional status, fatigue, cognitive complaints, quality of life, dyspnea, lower-limb endurance, and orthostatic tolerance over time. Safety is monitored throughout all follow-up visits. Approximately 40 participants meeting predefined eligibility criteria will be enrolled. This trial seeks to determine whether a single stellate ganglion block has an effect on persistent long-COVID symptoms compared with placebo.The results will help determine the therapeutic value of SGB in the management of long COVID and inform future research and clinical practice.

This description comes directly from the study's public registry record.

Talk to the study team

Marie-Claude Lehoux, Master's degree  ·  819 697-3333  ·  marie-claude.lehoux@ssss.gouv.qc.ca

Éva Mathieu, Ph.D  ·  819 697-3333  ·  eva.mathieu@ssss.gouv.qc.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Centre hospitalier affilié universitaire régionalTrois-Rivières, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07374562