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Study identifier: NCT07374354 Synced from ClinicalTrials.gov · July 29, 2026
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Preemptive Analgesia for Pain and Anxiety Control in Children With MIH

Condition: Pain and Anxiety in Children With MIH  ·  Sponsor: October University for Modern Sciences and Arts

PhaseNA
Planned participants46
Who can joinAll sexes, 6 Years to 12 Years
Healthy volunteersNo

About this study

This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with molar-incisor hypomineralization (MIH). MIH-affected teeth often present with hypersensitivity, difficulty in achieving adequate anesthesia, and increased dental anxiety, which complicates dental treatment. Participants aged 6-12 years with MIH will receive either ibuprofen syrup or placebo 30 minutes before treatment. Pain will be assessed using the FLACC Behavioral Pain Scale and Wong-Baker FACES scale, and anxiety will be evaluated through heart rate and oxygen saturation. The results will determine whether preoperative ibuprofen reduces intraoperative pain and improves anxiety control in this population.

This description comes directly from the study's public registry record.

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Locations (1)

October university of modern science and artsGiza, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07374354