Condition: Androgenetic Alopecia (AGA) · Sponsor: Shenzhen People's Hospital
This is a single-center, randomized, double-blind, placebo-controlled clinical trial designed to evaluate whether topical application of Lactobacillus reuteri can safely and effectively treat androgenetic alopecia. The study is based on the concept that balancing the scalp's microbial community may support hair follicle function. Participants will be randomly assigned to one of four groups receiving either active probiotic solution, inactivated probiotic solution (control for non-viable bacterial effects), a saline placebo, or the standard treatment 5% minoxidil solution for 12 months. Neither participants nor assessing clinicians will know the assigned treatment. The main goal is to measure improvement in hair count per square centimeter after one year. Additional measures include changes in hair thickness and quality. This research seeks to provide high-quality scientific evidence on a new microbiome-targeting approach, offering future patients and healthcare providers insights into a potential alternative or complementary treatment strategy for hair loss.
This description comes directly from the study's public registry record.
Jianglin Zhang · +86 13873143466 · zhang.jianglin@szgospital.com
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| Shenzhen People's Hospital | Shenzhen, Guangdong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07370519