Condition: Heart Failure · Diuretics · Sponsor: Cardiology Research UBC
Heart failure is a chronic condition that causes congestion and frequent hospitalizations. Diuretic doses are usually adjusted based on clinical judgment without an objective measure of response. This study will test the feasibility of using point-of-care urine sodium measurements to guide up-titration or down-titration of loop diuretics in ambulatory patients with heart failure. Participants will be assigned to one of three groups based on congestion status. Groups 1 and 2 will be randomized 1:1 to natriuresis-guided therapy or standard care. Group 3 will be observational. The 90-day pilot trial will evaluate feasibility, clinical outcomes, and usability of a urine sodium-guided titration strategy.
This description comes directly from the study's public registry record.
Natalie Bloch, MD · 604-875-4111 · natalie.blochisenberg@vch.ca
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| Vancouver General Hospital | Vancouver, British Columbia, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07369856