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Study identifier: NCT07368998 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer

Condition: Breast Cancer  ·  Sponsor: Hoffmann-La Roche

PhasePhase 2
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of inavolisib in combination with fulvestrant compared with inavolisib in combination with fulvestrant in participants with PIK3CA-mutated, HR-positive, HER2-negative locally advanced or metastatic breast cancer (LA/mBC) in the post-cyclin-dependent kinase inhibitor (CDKi) setting.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: WO46063 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (30)

Los Angeles Cancer NetworkLos Angeles, California, United StatesRecruiting
Astera Cancer Care East BrunswickEast Brunswick, New Jersey, United StatesRecruiting
Instituto de Oncologia de RosarioRosario, Santa Fe Province, ArgentinaRecruiting
Centro Oncologico KorbenCiudad Autonoma Buenos Aires, ArgentinaRecruiting
Hospital Privado - Centro Medico de CórdobaCórdoba, ArgentinaRecruiting
Centro Oncologico Riojano Integral (CORI)La Rioja, ArgentinaRecruiting
Hospital Provincial del CentenarioRosario, ArgentinaRecruiting
Centro Oncológico de ExcelenciaSan Juan, ArgentinaRecruiting
Blacktown HospitalBlacktown, New South Wales, AustraliaRecruiting
Coffs Harbour Health CampusCoffs Harbour, New South Wales, AustraliaRecruiting
Bendigo Cancer CentreBendigo, Victoria, AustraliaRecruiting
Cliniques Universitaires St-LucBrussels, BelgiumRecruiting

+ 18 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07368998