Condition: Chronic Kidney Disease (Stage 3-4) · Chronic Kidney Disease Mineral and Bone Disorder · Sponsor: University of Texas Southwestern Medical Center
The proposed pilot feeding study aims to explore novel pathways in phosphate metabolism and identify new biomarkers, as well as to develop a compound index for assessing phosphate overload with high validity and reliability. Investigators will address the following specific aims: 1). To explore novel pathways of phosphate metabolism and assess the influence of CKD status on these metabolic pathways. 2). To identify novel biomarkers for phosphate overload that reflect changes in dietary phosphorus intake. 3). To develop a compound phosphate overload index that measures dietary phosphorus intake with high validity and reliability. This study will provide novel insights into phosphate metabolism and the assessment of phosphate overload in CKD patients. This investigation aims to provide preliminary data to further studies for the development of reliable biomarkers in CKD patients, which could contribute significantly to early interventions and improve health outcomes.
This description comes directly from the study's public registry record.
Alexandra Hartman · 214-645-8294 · pack.utsw@utsouthwestern.edu
Paola Lanza, MD · 469-852-9550 · paola.lanza@utsouthwestern.edu
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| University of Texas Southwestern Medical Center | Dallas, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07368946