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Study identifier: NCT07368621 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effectiveness of Connective Tissue Graft With and Without Leukocyte Platelet Rich Fibrin on Peri-implant Soft Tissue Thickness Around Delayed Implants in Patients With Thin Gingival Phenotype: A Randomized Controlled Clinical Trial

Condition: Soft Tissue Thickness Around Delayed Implants in Patients With Thin Gingival Phenotype  ·  Sponsor: British University In Egypt

PhaseNA
Planned participants38
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

A stable soft and hard tissues around Osseo-integrated implants are very crucial. Soft tissue thickness around implants is crucial as it prevents peri-implant bone loss and enhance the esthetic outcomes. The treatment of thin tissue phenotype should be improved as the thin tissue phenotype will lead to plaque accumulation. There are some techniques that can increase the thickness of the peri-implant mucosa including connective tissue graft, platelet- rich fibrin and xenogeneic collagen matrix .Leukocyte and Platelet rich fibrin is a second generation platelet concentrate that was introduced by choukroun et al in 2001 after platelet rich plasma. PRF is the first source of autogenous blood derived growth factors harvested without the use of anticoagulants5. It contains various growth factors that are believed to contribute to periodontal regeneration. It promotes neovascularization and accelerated wound closing

This description comes directly from the study's public registry record.

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Locations (1)

The British University in EgyptCairo, Cairo Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07368621