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Study identifier: NCT07361263 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-Deficiency

Condition: AVP Deficiency · Diabetes Insipidus  ·  Sponsor: University Hospital, Basel, Switzerland

PhaseNA
Planned participants28
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersYes

About this study

The PHOENIX study aims to investigate whether oral estradiol valerate (EV) and ethinylestradiol (EE) can stimulate oxytocin (OXT) and neurophysin-1 (NP-1) release in humans. The goal is to assess their potential as a safe diagnostic stimulation test for oxytocin deficiency, particularly in patients with arginine vasopressin (AVP) deficiency.

This description comes directly from the study's public registry record.

Talk to the study team

Andi Nikaj, MD  ·  +41 61 328 57 43  ·  andi.nikaj@usb.ch

Ursula Gobrecht-Keller, MD  ·  +41 61 32 86028  ·  ursula.gobrecht@usb.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital BaselBasel, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT07361263