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Study identifier: NCT07361146 Synced from ClinicalTrials.gov · July 29, 2026
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A Comparative Study of Intradialytic vs. Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial

Condition: End-stage Renal Disease (ESRD) · Chronic Kidney Disease · Hemodialysis Patients  ·  Sponsor: Mohammad Arian

PhaseNA
Planned participants72
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

This randomized controlled trial aims to compare the effectiveness of two different timings of physical therapy for individuals undergoing hemodialysis: intradialytic (during dialysis) and pre-dialysis (before dialysis). The study seeks to determine which approach provides better improvements in physical function, quality of life, and biochemical outcomes such as hemoglobin and electrolyte levels. A total of 72 adult participants with end-stage renal disease (ESRD) receiving hemodialysis will be randomly assigned to one of two groups. Both groups will receive standardized educational sessions on the benefits and safety of exercise before beginning the intervention. Participants in the intradialytic group will perform supervised exercises during their dialysis sessions, while those in the pre-dialysis group will complete similar exercises before their dialysis sessions. Each participant will undergo the intervention twice per week for 12 weeks. Primary outcomes include physical function, assessed using the Six-Minute Walk Test and the Five Times Sit-to-Stand Test. Secondary outcomes include hemoglobin levels, electrolyte balance, and health-related quality of life measured by the KDQOL questionnaire. The study will be conducted at Mubarak Al-Abdullah Al-Jaber Al-Sabah Dialysis Center, Kuwait, following ethical approval from the Ministry of Health Research Ethics Committee. The results are expected to inform best practices for integrating physical therapy into dialysis care …

This description comes directly from the study's public registry record.

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Locations (1)

Mubarak Al-Abdullah Al-Jaber Al-Sabah Dialysis CenterHawalli, KuwaitRecruiting

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Source record: clinicaltrials.gov/study/NCT07361146