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Study identifier: NCT07358754 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor

Condition: Fibromyalgia  ·  Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

PhaseN/A
Planned participants60
Who can joinFemale, 18 Years to 50 Years
Healthy volunteersYes

About this study

Fibromyalgia is a chronic pain syndrome characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive symptoms. Central sensitization is considered a key mechanism in the pathophysiology of fibromyalgia; however, the underlying biological markers have not been fully clarified. Brain-derived neurotrophic factor (BDNF) and S100B protein have been suggested to play roles in neuroinflammation and central pain processing. This observational, cross-sectional study aims to evaluate serum S100B and BDNF levels in patients with fibromyalgia and to investigate their relationship with central sensitization and sleep quality. Serum biomarker levels and clinical assessment scales will be compared between patients with fibromyalgia and healthy controls.

This description comes directly from the study's public registry record.

Talk to the study team

Zeynep Karakuzu Güngör, M.D  ·  905077750375  ·  zeynepkarakuzu@hotmail.com.tr

Always discuss trial participation with your own doctor first.

Locations (1)

Kanuni Sultan Süleyman Training and Research HospitalIstanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07358754