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Study identifier: NCT07358078 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

Condition: Transthyretin Amyloidosis With Cardiomyopathy  ·  Sponsor: Alnylam Pharmaceuticals

PhaseN/A
Planned participants2000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with vutrisiran in routine clinical care * Describe treatment patterns of adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess health-related quality of life (HRQOL) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess healthcare resource use (HCRU) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care Compare the long-term effectiveness of vutrisiran versus other approved ATTR-CM treatments in routine clinical care

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trial Information Line  ·  1-877-ALNYLAM  ·  clinicaltrials@alnylam.com

Clinical Trial Information Line  ·  1-877-256-9526  ·  clinicaltrials@alnylam.com

Always discuss trial participation with your own doctor first.

Locations (4)

Clinical Trial SiteNaples, Florida, United StatesRecruiting
Clinical Trial SiteBoston, Massachusetts, United StatesRecruiting
Clinical Trial SiteNew Brunswick, New Jersey, United StatesRecruiting
Clinical Trial SiteMemphis, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07358078