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Study identifier: NCT07357597 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

Condition: Stomatitis  ·  Sponsor: AstraZeneca

PhasePhase 4
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, single-arm study of prophylaxis for Dato-DXd-related stomatitis in eligible patients with metastatic or inoperable locally recurrent breast cancer or locally advanced or metastatic Epidermal Growth Factor Receptor-Mutated (EGFRm) non-small cell lung cancer.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (39)

Research SiteTucson, Arizona, United StatesWithdrawn
Research SiteHot Springs, Arkansas, United StatesRecruiting
Research SiteLittle Rock, Arkansas, United StatesRecruiting
Research SiteDuarte, California, United StatesNot Yet Recruiting
Research SiteGlendale, California, United StatesNot Yet Recruiting
Research SiteLakewood, California, United StatesNot Yet Recruiting
Research SiteLong Beach, California, United StatesRecruiting
Research SiteTorrance, California, United StatesNot Yet Recruiting
Research SiteWashington D.C., District of Columbia, United StatesWithdrawn
Research SitePlantation, Florida, United StatesNot Yet Recruiting
Research SiteAthens, Georgia, United StatesRecruiting
Research SiteBoise, Idaho, United StatesWithdrawn

+ 27 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07357597