Condition: Postoperative Delirium (POD) · Postoperative Pain · PONV · Sponsor: Istanbul University - Cerrahpasa
This study aims to investigate the effect of target-controlled infusion using the Eleveld pharmacokinetic model compared with manually controlled total intravenous anesthesia on the incidence of postoperative delirium in patients undergoing supratentorial surgery. Propofol and remifentanil are administered using either target-controlled or manual infusion techniques according to the study protocol. Secondary objectives include comparisons of intraoperative anesthetic consumption, hemodynamic responses, recovery profiles, postoperative pain, and postoperative nausea and vomiting between the two anesthesia strategies. The study seeks to evaluate whether target-controlled infusion provides improved anesthetic management and postoperative outcomes compared with manual total intravenous anesthesia.
This description comes directly from the study's public registry record.
Ali Okuyan, MD · +905073736874 · aliokuyan@gmail.com
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| Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine | Istanbul, Bakırköy, Turkey (Türkiye) | Not Yet Recruiting |
| Cerrahpaşa Tıp Fakültesi Murat Dilmener Hastanesi | Istanbul, Istanbul, Turkey (Türkiye) | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07357480