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Study identifier: NCT07355205 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

First-Line Ipilimumab Plus Nivolumab and Nogapendekin Alfa Inbakicept (N-803) in Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer Stage IV · Non-small Cell Lung Cancer Recurrent  ·  Sponsor: Washington University School of Medicine

PhasePhase 1/Phase 2
Planned participants26
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a single center, phase Ib/II study combining an anti-PD-1 antibody and an anti-CTLA-4 antibody with IL-15. It is testing the hypothesis that the addition of nogapendekin alfa inbakicept to nivolumab and ipilimumab will augment the clinical activity of those two drugs.

This description comes directly from the study's public registry record.

Talk to the study team

Giordano Fabricio Cittolin Santos, MD, PhD  ·  314-273-4731  ·  cgiordano@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07355205